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  • chan品型号:Oxylet
  • chan品厂商:dong物代谢监cexi统
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简单介绍:
Panlabdong物代谢xi统Oxylet System是公葂i膟an究代谢xing为的*好的xi统之一,quan球*大的dong物实验仪器供应商Harvard和Stoelting,都指定Panlab的dong物代谢celiangfen析xi统Oxyletxi统为唯壹的代谢yan究设备,推荐给yan究者。dong物代谢celiangfen析xi统由不tong的chuan感器组cheng,bing为每一种dong物都整合了大liang的信息。dong物代谢celiangfen析xi统tong时大鼠和小鼠在笼的居住环境中监ce几组生理和xing为canshu。
详情介绍:

型号:Oxylet
品牌:panlab



dong物代谢xi统由不tong的chuan感器组cheng,bing为每一种dong物都整合了大liang的信息。dong物代谢celiangfen析xi统可以自dongdi,无干涉di长期对大liang的dong物进xing监ce(24小时甚至连xu几天)。dong物代谢celiangfen析xi统tong时大鼠和小鼠在笼的居住环境中监ce几组生理和xing为的canshu。
 
 
dong物代谢xi统Oxylet 是一套模块化的xi蚦hang瑈an究者可选择性di对dong物的呼xi代谢(O2消hao和CO2chan出)、饮食yu饮shuiliang、运donghuo衴uan驼玖?ing为等进xingfen别监ce,bingjiangyan究shu据结合起来进xingfen析。

    dong物代谢xi统Oxylet的dong物笼采yongAllentown Caging Equipment(ACE)生chan的标准dong物笼体bing进xing进一步jia工。笼体耐高温高压处理,便于**清理。笼体以wai的其它配jian:mi闭笼盖、网格di板、饮食和饮shui槽等,都可以单du定制。特别是,du特设计的mi闭笼盖可以gai变dong物笼的空间,使一套呼xi检cexi统可以tong时适yong于大鼠和小鼠实验。

dong物代谢xi统Oxylet可监cecanshu包括

饮shuiyu喂蔯hang╯huliang和模式)

新陈代谢的表xian(氧气的消hao和二氧化碳的排出)

在居住笼中的huodong

转轮跑台等huodong(可选)

1.饮食yu饮shui监ce:

   Panlab自主yan发的灵minzhonglichuan感技术取代了chuan统的wai置电子秤来对dong物饮食饮shuiliang进xing监ce。chuan感器、电信号放大器和shu模转huan器等灵minyuanjian被wanquan整合在笼体xia部的金属底座(Platform)na。Platform面板提供了wan整的操作按钮,bing有LED显示屏显示当前的shu据。饮蔯hang⒁鹲hui槽的zhongliang变化,通过巧妙设计的导li支架被平台na的chuan感器統ou眨?渲惺澄锖蛃hui的celiang精度fen别高达0.02g和0.01g!实际celiang中的xi统raodongwu差zhi也fen别控制在0.02g和0.01ml以na!饮食饮shui监ce达到如此高的**度和稳定性在市chang中****!
  
饮食槽和饮shui槽fen别采yong了巧妙的回收设计,jiangdong物进食过程謝ing孤┑氖澄锖蛃hui回收bing从真实shu据中自dong去除,大大提高了长期记lu的shu据精度。

综合以shang性能特点,使Panlab Oxyletxi统可以真正yong于小鼠的摄入代谢长期监ce。

为了满zu特定的yan究需要,如yan究dong物对不tong实物的偏好和饮食模式等,其中的饮食和饮shui槽还可以fen别互相替huan,例如gai装两ge饮食槽、两ge饮shui槽。




2.呼xi代谢检ce: 

   dong物代谢xi统Oxylet呼xi代谢的celiang原理是通过检cedong物呼xi气体中O2和CO2cheng穤hi谋浠?浣拥募扑愠鰀ong物能liang的消hao,   这也是目前实验室yong于啮齿类dong物能liang代谢检cechangyong的fang式。
  
 dong物代谢celiangfen析xi统Oxylet的气体liuliang控制器保证在mi闭笼体中维持恒定的空气liuliang,liu速可以在0至20L/minna连xu**di设定。liu速的**diao节,保证了无论dong物处于剧烈运dong还是xiu眠zhuang态,都可以得到十fen觴ingУ暮魓i代谢shu据。该liuliang控制器襤ua阄?通道或4通道设计,例如一款4通道Oxyletliuliang控制器可以du立difen别控制4ge笼体的空气liudong。通过du特的笼盖设计,使笼体na的空间根据实验dong物的不tong而gai变,fen别适yong于大鼠和小鼠。

  
     dong物代谢xi统主要特点: 

先进化设计dong物代谢yan究xi统

市面*变通的体xi

硬ruanjian设计you好,操作简便

标准饲yang笼提供dong物舒适环綾hang?蛊淞齨axing为正chang

所有饲yang笼无需作任何修gai

小鼠yu大鼠组合xi蚦hang?山鴛ing**的yan究

饮shui取食xing为

niao液yu粪便的chan生liang

间接liang热,可对dong物呼xi代谢进xingyan究(包括O2消hao,CO2chan生,呼xi絟uan籰v,笼na温度变化等)

dong物在笼na的运dong监ce和记lu

转轮运dong

连xushuri进xing短期/长期监ce

能多zhidong物tong时检ce

得到食物和液体消haoliang,**到0.01gml,tong时能记lu排粪和排niaoliang


xi统配合dong物代谢celiangfen析xi统ruanjian可进xing实验设计、shu据记lu和fen析过程。

dong物代谢监cexi统有自己的标准组cheng部fen。这些部fen模块化di结合和组cheng起来,bing根据您不tong的需要为您的keyan提供觴ingУ墓ぞ撄/span>


 


经过liuliang控制的气liu被采样输入至xi统中*核心的部jian——气体chengfenfen析仪。fen析仪中安放了灵min的guang电二极管氧气探头、和红wai感应二氧化碳探头来精准监控气体cheng穤hi膅ai变,采集精度达到*高的0.01%。该xi统还能在一些特殊的yan究chang合使yong,如新生大鼠的微弱呼xi代谢检ce、于Treadmill跑步机运dongtong步的能liang消hao检ce等。

Oxyletruanjian能自dong计算平均氧气消hao(VO2)、平均二氧化碳排liang(VCO2)、以及呼xi商(RQ=VCO2/VO2),bing自dong按以xia公式推算huan能lv:
EE=(3.815+(1.232xRQ))xVO2x1.44

• 热liang检ce仪能celiangO2 消haoliang(VO2), CO2chan生liang (VCO2), 呼xi絟uan籰v(RER), 热liang的chan生以及温度。
• liang热计直接celiang簍ong⒋媸笛槭奔鋜i期,笼naO2 和 CO2 浓度,空气liu速和温度(以每ge笼为单位),计算VO2, VCO2,RER 和 热liang。
• liang热计特殊的dong物笼能连接空气进气管,出气管,du立的样品连接以及可选的温度chuan感器。
• 呼xi代谢检ce仪高精度chuan感器能准确celiangO2, CO2 浓度,温度和气liu控制。


3.运donghuo衴uan驼玖ⅲ≧earing)监ce

   dong物代谢celiangfen析xi统Oxyletxi统通过位于笼体底部四脚的zhendongchuan导装置以及位于Platformshang相应位置的运dongchuan感器感shoudong物运donghuo性;通过架设du立的一秠uan靪ai感应条来监cedong物站立xing为。平台na的运dongchuan感器能感shou到dong物非chang微小的huodong,可**diyong于小鼠huodong监ce。红wai感应条作为附jia模块,可以为有站立xing为yan究需要者选购。dong物huodong性shu据可以直接导入计算机中由专men的ruanjian模块METAACTfen析和生chengshu据图表,也可以在每ge笼子xiafangPlatform的LED显示屏中实时查看到。

两种运dongchuan感器:

-- 在X,Y,Z三维fang向shang,红waiguang柱chuan感器支架包wei饲yang笼

---在笼盖顶端,安装红wai热chuan感器,yong于监ce总运dong

 

为实xian运dongceliang,dong物笼放在红waiguang柱chuan感器支架na。guang柱chuan感器安装在X和Yfang向shang,此wai可以补chong可diao整的高度Z(垂直于X),yong于站立指示器。guang柱被截秞i膠huang态随着dong物的运dong而变化。每ge变化都jiang登记为一次计shu。这意味着如果长久性截断guang柱jiang不被计shu。

 

通过安装在笼盖蓌i暮靪ai位移chuan感器,能fang便的celiang饲yang笼na的大小鼠或其他小型实验dong物的总运dong。可以在任何guangxian条jianxiaceliang运dong。celiang甚謑iang梢栽趒uan黑的情况xia进xing。chuan感器记lu一ge或多ge物体运dong,是通过感应体热图进xing的,也就是说通过红waifu射,然后jiang其空间位移作为时间的函shu。这种fang法能确定笼na的运dongbing进xing定liang。这甚至能记lu一gezhili时几ge毫秒的运dong。



dong物代谢xi统订购信息

您可以任意定制满zu您yan究需要的Oxylet代谢检cexi统

您需要多少zhidong物tong时检ce?e渲卸嗌賨hi大鼠、多少zhi小鼠?
您需要检ce那些shu据?e渲卸嗌賨hi需要呼xi代谢检ce?多少zhi需要饮食饮shui监ce?
您需不需要为特殊形态的食物或饮料(粉zhuang食物、zhan稠液体)制定饮shui槽或饮食槽?
您需不需要开展2种食物或2种饮義i钠?脃an究?
您需不需要监cedong物的站立xing为?
您需不需要yong于跑步机TreadMill或者yong于新生大鼠的呼xi代谢监ce?
非chang期待您告诉我men您的需qiu!

 
 
使yong我men的dong物代谢celiangfen析xi统发表的wen章:

 

  • Andrade JM et al. (2014) Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet. Eur J Nutr. 2014 Jan 28. In press (mice, Brazil)
  • Bargut TC et al. (2014) Effects of a diet rich in n-3 polyunsaturated fatty acids on hepatic lipogenesis and beta-oxidation in mice. Lipids. 2014 May;49(5):431-44. (mice, Brazil)
  • Bojados M et al (2014) The long-term consequences of the exposure to increasing gravity levels on the muscular, vestibular and cognitive functions in ***** mice. Behav Brain Res. 2014 Feb 7. In press (treadmill, mice, France)
  • Cappelli AP et al. (2014) Taurine-induced insulin signalling improvement of obese malnourished mice is associated with redox balance and protein phosphatases activity modulation. Liver Int. 2014 May;34(5):771-83. (mice, Brazil)
  • Fortunato G et al. (2014) Recovery of pulmonary structure and exercise capacity by treatment with granulocyte-colony stimulating factor (G-CSF) in a mouse model of emphysema. Pulm Pharmacol Ther. 2014 Apr;27(2):144-9. (mice, Brazil)
  • Gaigé S et al. (2014) Modification of energy balance induced by the food contaminant T-2 toxin: a multimodal gut-to-brain connection. Brain Behav Immun. 2014 Mar;37:54-72. (France)
  • Makki K et al. (2014) Beneficial metabolic effects of rapamycin are associated with enhanced regulatory cells in diet-induced obese mice. PLoS One. 2014 Apr 7;9(4):e92684. (mice, France, UK)
  • Nunes-Silva A et al (2014) Treadmill Exercise Induces Neutrophil Recruitment into Muscle Tissue in a Reactive Oxygen Species-Dependent Manner. An Intravital Microscopy Study. PLoS One. 2014 May 5;9(5):e96464. (rat, Brazil)
  • Tha?s R et al. (2014) Acute oral metformin enhances satiation and activates brainstem nesfatinergic neurons. Obesity (Silver Spring). In press (mice, France)
  • Casuso Ra et al. (2013) Ergogenic effects of quercetin supplementation in trained rats. J. Int. Society of Sports Nutrition. 10:3-7 (LE8710R, VO2 mx, exhaustion, rat, Spain)
  • Cettour-Rose P et al. (2013) Quinine controls body weight gain without affecting food intake in male C57BL6 mice. (mice, Switzerland, Japan).
  • Coutinho GVP et al. (2013) Intrauterine protein restriction combined with early postnatal overfeeding was not associated with *****-onset obesity but produced glucose intolerance by pancreatic dysfunction. Coutinho et al. Nutrition & Metabolism 2013, 10:5. (rat, Brazil)
  • Fortunado G et al. (2013) Recovery of pulmonary structure and exercise capacity by treatment with granulocyte-colony stimulating factor (G-CSF) in a mouse model of emphysema. Pulmonary Pharmacology & Therapeutics. In press (mice, treadmill, Brazil).
  • Gaigé S et al. (2013) Modification of energy balance induced by the food contaminant T-2 toxin: A multimodal gut-to-brain connection. Brain Behav Immun. 2013 Dec 16. In press (France)
  • Hyun-Ju K et al. (2013) Metformin decreases meal size and number and increases c-Fos expression in the nucleus tractus solitarius of obese mice. Physiology & Behavior. 110-111:213-220. (Obese mice, Republic of Korea.)
  • Ikonomov OC et al. (2013) Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity and hyperinsulinemia but not muscle fiber-type switching. Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E119-31. (mouse, USA)
  • Kim HJ et al. (2013) Central administration of metformin into the third ventricle of C57BL/6 mice decreases meal size and number and activates hypothalamic S6 kinase. American Journal of Physiology - Vol. 305no. R499-R505. (mouse, Korea)
  • Kim HJ et al. (2013) Metformin decreases meal size and number and increases c-Fos expression in the nucleus tractus solitarius of obese mice. Physiology & Behavior, Volumes 110–111. (mouse, Korea)
  • Kim YJ et al. (2013) Longterm supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in highfat fed mice. Molecular Nutrition & Food Research, Volume 57, Issue 11, pages 1988–1998 (mouse, Korea)
  • Larocca TF et al. (2013) Transplantation of adipose tissue mesenchymal stem cells in experimental chronic chagasic cardiopathy. Arq. Bras. Cardiol. vol.100 no.5 (mouse, Brazil)
     
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